< Back to Faculty

Dr Valentina Tassinari

Email: valentina.tassinari@uniroma2.it
Bldg F Nord, IV floor – room F482
Faculty of Medicine and Surgery
Department of Experimental Medicine
University of Rome “Tor Vergata”
Via Montpellier 1 – 00133 Rome | Italy
ORCID |  Scopus

Short biographical sketch of Dr Valentina Tassinari

Dr Valentina Tassinari is a biologist with a PhD in Medical Biotechnology and Translational Medicine that she got at University of Rome Tor Vergata.  She worked as a postdoctoral researcher at Ospedale Pediatrico Bambino Gesù and Sapienza University, in Rome. Her main scientific interest is focused on the understanding the role of the RNA editing enzymes, Adenosine Deaminase acting on RNA (ADARs) in tumor progression. ADARs catalyzes the C6 deamination of adenosine (A) to produce inosine (I) in double-stranded RNAs (dsRNAs). This process, called A-to-I RNA editing, occurs in coding and non-coding region of the transcript, affecting its stability or coding, as I is read as G during translation. ADARs also regulate the transcriptome via editing-independent activity, such as RNA binding, and direct protein interactions. A deregulation of ADARs expression and/or activity has been implicated in cancer development and progression. Moreover, ADAR1 controls interferon signaling via dsRNAs sensors, which translates to an immunosuppressive effect in the context of cancer. 

See a full CV of Dr Valentina Tassinari.

< Back to Faculty