Dottorato in Biochimica e Biologia Molecolare | Roma | Tor Vergata

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Prof Alessia Angelin

Short biographical sketch of Prof Alessia Angelin

Dr. Alessia Angelin obtained her Master’s Degree in Biological Sciences from the University of Padua, Italy, with a thesis on the biochemical characterization of mitochondrial function under the supervision of Prof. Paolo Bernardi. At the University of Padua, she also obtained her PhD in Molecular and Cellular Biology and Pathology, working on the role of mitochondria in human muscular dystrophies, again under the supervision of Prof. Bernardi.  

Dr. Angelin has 15 years of international research experience in biochemistry and biomedical sciences, and her research primarily focuses on the physiology of mitochondria in human diseases. During these years, she worked as a postdoctoral scholar at the University of Padova, the University of California-Irvine (USA), and the Children’s Hospital of Philadelphia (USA) under the supervision of Prof. Douglas C. Wallace.  Dr. Angelin consolidated her position as a Senior Research Scientist at the Center for Mitochondrial and Epigenomic Medicine, directed by Prof. Wallace, at the Children’s Hospital of Philadelphia. She investigated the mitochondrial contribution to the pathophysiology of human cardiomyopathy and muscular dystrophy and recently developed an AAV-based gene therapy for treating human mitochondrial cardiac disorder. Over the years, her scientific interests have expanded to include the role of mitochondria in immune deficiencies and infection, metabolic diseases, and cancer.

In 2024, she returned to Italy as an Assistant Professor in Biochemistry at the University of Rome Tor Vergata, School of Medicine.  In Prof. Eleonora Candi’s laboratory, she studies the metabolic changes that occur in the transformation of neoplastic cells and tumor proliferation using cellular and murine models with biochemical techniques and omics characterization, with particular attention to the role of mitochondria.

Currently, Dr. Angelin is mainly involved in two projects: (i) characterizing the role of p63 in regulating muscular differentiation and (ii) investigating the contribution of the polyol pathway in tumor development. Dr. Angelin has published 32 peer-reviewed articles and attended about 40 scientific conferences, several as an invited speaker.  Dr. Angelin teaches Biochemistry in the Pharmacy Degree Course

See a full CV of Prof Alessia Angelin.

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